Just out in eLife , our paper on early cardiac lineage specification and patterning changes a lot about how we view the origins of the heart, and how chamber morphogenesis is established. This work incorporates clonal lineage tracing, classic embryology, and inventive dual lineage tracing, to redefine when cardiac precursors are specified and allocated to specific chambers of the heart.
Devine W.P., Wythe J.D., George M., Koshiba-Takeuchi K., & Bruneau B.G. (2014) Early patterning and specification of cardiac progenitors in gastrulating mesoderm. eLife published online 10/08/14 http://dx.doi.org/10.7554/eLife.03848